Product Description

Brp44L Rabbit Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: ES1793-50, ES1793-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: The protein encoded by this gene is part of an MPC1/MPC2 heterodimer that is responsible for transporting pyruvate into mitochondria. The encoded protein is found in the inner mitochondrial membrane. Defects in this gene are a cause of mitochondrial pyruvate carrier deficiency. Several transcript variants, some protein coding and one non-protein coding, have been found for this gene. [provided by RefSeq, Aug 2012],

Reactivity: Human, Mouse, Rat

Host: Rabbit

Applications: WB, IHC, IF, ELISA

Alternate Names: MPC1, BRP44L, CGI-129, HSPC040, PNAS-115, Mitochondrial pyruvate carrier 1, Brain protein 44-like protein

Clonality: Polyclonal

Immunogen: The antiserum was produced against synthesized peptide derived from human BRP44L. AA range:11-60

Isotype: IgG

Target: Brp44L

Specificity: Brp44L Polyclonal Antibody detects endogenous levels of Brp44L protein.

Dilution: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration: 1 mg/ml,

Formlation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Expression: Placenta, Promyelocytic leukemia, Skeletal muscle, Umbilical cord blood,

Observed Band (KD): 12kD

Fields: Diabetic cardiomyopathy

Function: Similarity: Belongs to the UPF0041 (0-44) family

Subcellular Location: Mitochondrion inner membrane, Multi-pass membrane protein

Storage and Stability: -20°C/1 year

Gene Name: MPC1

Protein Name: Mitochondrial pyruvate carrier 1

Mouse Gene ID: 55951

Mouse SwissProt Number: P63030

Rat Gene ID: 171087

Rat SwissProt Number: P63031

Research Use Only