c-Fos Monoclonal Antibody (6A3) - BT-MCA0239

c-Fos Monoclonal Antibody (6A3)

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-MCA0239-20, BT-MCA0239-50, BT-MCA0239-100

Citations, Manuals and MSDS Available upon request.

Background: The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation. In some cases, expression of the FOS gene has also been associated with apoptotic cell death.

Research Areas: Epigenetics and nuclear signaling; Neuroscience; Cancer

Target Protein: FOS

Applications: WB, IHC-p, IF

Reactivity: Human,Rat,Mouse

Clonality: Monoclonal

Host: Mouse

Isotype: IgG

Full Product Name: Proto-oncogene c-Fos

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

UniProt Accession: Human: P01100; Mouse: P01101; Rat: P12841

Synonyms: Proto-oncogene c-Fos; Cellular oncogene fos; G0; G1 switch regulatory protein 7

GeneID: Human: 2353

Research Use Only