c-Fos Rabbit pAb
Sizes: 20μL, 100μL
Catalogue Numbers: A0236-20, A0236-100
Citations, Manuals and MSDS Available upon request.
Background: The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation. In some cases, expression of the FOS gene has also been associated with apoptotic cell death.
Category: Polyclonal Antibodies
Applications: WB, IP, ELISA
Cross-reactivity: Human
Protein Weight: 41kDa
Observed Molecular Weight: 55-60kDa
Immunogen: Recombinant protein (or fragment)
Species: Human
GeneID: 2353
SWISS: P01100
Alternate Names: p55; AP-1; C-FOS; c-Fos
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
Recommended Dilutions: WB, 1:500 - 1:1000 IP, 0.5μg-4μg antibody for 200μg-400μg extracts of whole cells ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Research Areas: Epigenetics Nuclear Signaling, Transcription Factors, Protein phosphorylation, Cancer, Tumor biomarkers, Signal Transduction, ErbB-HER Signaling Pathway, MAPK-Erk Signaling Pathway, Immunology Inflammation, T Cell Receptor Signaling Pathway, Neuroscience, Cell Type Marker, Neuron marker.
NCBI Alias: FOS
Research Use Only