C5AR1 Rabbit pAb
Sizes: 20μL, 100μL
Catalogue Numbers: A1900-20, A1900-100
Citations, Manuals and MSDS Available upon request.
Background: Enables G protein-coupled receptor activity and complement component C5a receptor activity. Involved in several processes, including complement component C5a signaling pathway; mRNA transcription by RNA polymerase II; and positive regulation of ERK1 and ERK2 cascade. Located in apical part of cell and basolateral plasma membrane. Biomarker of Alzheimer's disease; asthma; chronic obstructive pulmonary disease; rhinitis; and severe acute respiratory syndrome.
Category: Polyclonal Antibodies
Applications: WB, IHC-P, ELISA
Cross-reactivity: Human, Mouse, Rat
Protein Weight: 39kDa
Observed Molecular Weight: 45kDa
Immunogen: Recombinant protein (or fragment) .
Species: Human
GeneID: 728
SWISS: P21730
Alternate Names: C5A; C5AR; C5R1; CD88; C5AR1
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.09% sodium azide 50% glycerol pH7.3
Recommended Dilutions: WB, 1:500 - 1:1000 IHC-P, 1:50 - 1:200 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Research Areas: Cancer, Signal Transduction, G protein signaling, G-Protein-Coupled ReceptorsGPCR, Endocrine Metabolism, Immunology Inflammation, CDs, Cell Intrinsic Innate Immunity Signaling Pathway.
NCBI Alias: C5AR1
Research Use Only