Product Description

CA IX/Carbonic Anhydrase IX Mouse Monoclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: EM1076-50, EM1076-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: The carbonic anhydrases (or carbonate dehydratases) form a family of enzymes that catalyze the rapid interconversion of carbon dioxide and water to bicarbonate and protons (or vice versa), a reversible reaction that occurs rather slowly in the absence of a catalyst. CAIX is considered to be one of the best cellular biomarkers of hypoxia. Furthermore, recent studies examining the association between CAIX levels and various clinicopathological outcomes suggest that CAIX expression may also be a valuable prognostic indicator for overall survival. Antibodies against CAIX serve as excellent excellent biomarkers of hypoxic regions in many solid tumors.

Reactivity: Human

Host: Mouse

Applications: WB, IHC, IP

Alternate Names: CA9, CAIX, Carbonate dehydratase IX, Carbonic anhydrase 9, carbonic anhydrase IX, G250, Membrane antigen MN, MN, P54/58N, pMW1, RCC associated antigen G250

Clonality: Monoclonal

Immunogen: Synthetic Peptide

Isotype: IgG1

Dilution: WB 1:3,000 IP 1:200  IHC 1:100-200

Concentration: 1mg/mL,

Observed Band (KD): 35-38kDa

Subcellular Location: Nucleus Nucleus, nucleolus Cell membrane Cell projection, microvillus membrane

Storage and Stability: PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

Research Use Only