Product Description

CA VA Rabbit Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: ES1813-50, ES1813-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. CA VA is localized in the mitochondria and expressed primarily in the liver. It may play an important role in ureagenesis and gluconeogenesis. CA5A gene maps to chromosome 16q24.3 and an unprocessed pseudogene has been assigned to 16p12-p11.2. [provided by RefSeq, Jul 2008],

Reactivity: Human

Host: Rabbit

Applications: WB, ELISA

Alternate Names: CA5A, CA5, Carbonic anhydrase 5A, mitochondrial, Carbonate dehydratase VA, Carbonic anhydrase VA, CA-VA

Clonality: Polyclonal

Immunogen: The antiserum was produced against synthesized peptide derived from human CA5A. AA range:171-220

Isotype: IgG

Target: CA VA

Specificity: CA VA Polyclonal Antibody detects endogenous levels of CA VA protein.

Dilution: Western Blot: 1/500 - 1/2000. ELISA: 1/40000. Not yet tested in other applications.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration: 1 mg/ml,

Formlation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Expression: Liver, Umbilical cord,

Observed Band (KD): 35kD

Fields: Nitrogen metabolism, Metabolic pathways

Function: Catalytic Activity: H(2)CO(3) = CO(2) + H(2)O
Cofactor: Zinc
Function: Reversible hydration of carbon dioxide
Similarity: Belongs to the alpha-carbonic anhydrase family

Subcellular Location: Mitochondrion

Storage and Stability: -20°C/1 year

Gene Name: CA5A

Protein Name: Carbonic anhydrase 5A mitochondrial

Mouse SwissProt Number: P23589

Research Use Only