Product Description

Calmodμlin (Phospho-T80/S82) Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS66189-50, BS66189-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: Calmodμlin is a ubiquitously expressed small protein mediating many cellμlar effects such as short-term and long-term memory, nerve growth, inflammation, apoptosis, muscle contraction and intracellμlar movement. Upon binding of four Ca2+ ions, calmodμlin undergoes conformational changes, allowing this complex to bind to and activate many enzymes including protein kinases, protein phosphatases, ion channels, Ca2+ pumps, nitric oxide synthase, inositol triphosphate kinase, and cyclic nucleotide phosphodiesterase. Since calmodμlin binds Ca2+ in a cooperative fashion, small changes in cytosolic Ca2+ levels lead to large changes in the level of active calmodμlin and its target proteins.

Category: Primary Antibody

Reactivity: Human, Mouse, Rat

Host: Rabbit

Applications: WB, IF/ICC, IHC

Alternate Names: CALM, CAM, CAM1, CAM2, CAMB, CALML2, CAM3, CAMC, CAMIII, Calmodμlin, CaM

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Phosphorylation

Immunogen: KLH-conjugated synthetic phosphopeptide corresponding to residues surrounding T80/S82 of human Calmodμlin protein.

Dilution: WB: 1:500-1:1000
IF/ICC: 1:100-1:500
IHC: 1:100-1:200

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: Recognizes endogenous levels of Calmodμlin protein only when phosphorylated at T80/S82.

Molecular Weight: ~ 17 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: P62158

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Research Use Only