CAPN3 Polyclonal Antibody - E-AB-92137

CAPN3 Polyclonal Antibody

Sizes: 60μL, 120μL, 200μL

Catalogue Numbers: E-AB-92137-60, E-AB-92137-120, E-AB-92137-200

Citations, Manuals and MSDS Available upon request.

Abbreviation: CAPN3

Target Synonym: CAPN3; CANP3; CANPL3; LGMD2; LGMD2A; nCL-1; p94; calpain-3

Conjugation: Unconjugated

Host: Rabbit

Species Reactivity: Human, Mouse, Rat

Application: WB

Isotype: IgG

Clonality: Polyclonal

UNIProt ID: P20807

Background: Calpain, a heterodimer consisting of a large and a small subunit, is a major intracellular protease, although its function has not been well established. This gene encodes a muscle-specific member of the calpain large subunit family that specifically binds to titin. Mutations in this gene are associated with limb-girdle muscular dystrophies type 2A. Alternate promoters and alternative splicing result in multiple transcript variants encoding different isoforms and some variants are ubiquitously expressed.

Concentration: 1mg/mL

Immunogen: Recombinant fusion protein of human CAPN3

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification Method: Affinity purification

Dilution: WB 1:500-1:2000

Calculated MW: 18kDa/35kDa/84kDa/93kDa/94kDa

Observed MW: 110kDa

Storage: -20°C/One year. Avoid freeze / thaw cycles.

Shipping: Ice bag

Research Use Only