Product Description

Carboxylesterase (CES) Activity Colorimetric Assay Kit

Sizes: 48T, 96T

Catalogue Numbers: E-BC-K579-M-48, E-BC-K579-M-96

Lead times: 2-3 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Test Principle: Carboxylesterase (CES) is a polymeric protein that can catalyze the hydrolysis of carboxylate, thioester, carbamate and amide esters. CES can release effective drugs from some insoluble carboxylate prodrugs through hydrolysis reaction according to its hydrolysis characteristics. Secondly, due to its high catalytic efficiency and high specificity, CES can also regulate various metabolic functions (metabolism of ester substances, gene expression, material transport and detoxification, etc.). Therefore, detecting the activity of CES is of great significance for the early diagnosis of cancer and the research of biomedicine. CES catalyzed substrate reaction to produce chromogenic substance has maximum absorption at wavelength 405 nm, and CES enzyme activity is calculated by measuring OD value at 405 nm.

Abbreviation: CES

Research Areas: Glycolysis and Lipid Metabolism

Result Type: Enzyme activity

Detection Instrument: Microplate reader

Detection Type: Colorimetric method

Detection Range: 0.3-168.4 U/L

Tested Sample Types: Serum;Plasma;Animal tissue;Cell

Assay Length: 1 h

Sensitivity: 0.3 U/L

Inter cv: 2.7-11.0%

Intra cv: 1.8-5.1%

Research Use Only