Product Description

Carboxypeptidase B2 Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: E-AB-40640-50, E-AB-40640-100

Citations, Manuals and MSDS Available upon request.

Abbreviation: CPB2

Target Synonym: Carboxypeptidase B2; Carboxypeptidase U; CPU; Plasma carboxypeptidase B; pCPB; Thrombin-activable fibrinolysis inhibitor; TAFI; CPB2

Conjugation: Unconjugated

Host: Rabbit

Species Reactivity: Human

Application: WB

Isotype: IgG

Clonality: Polyclonal

UNIProt ID: Q96IY4

Background: CPB2 (Carboxypeptidase B2; also CPU and TAFI) is a secreted, 50-60 kDa glycoprotein member of the peptidase M14 family of enzymes. It is expressed by hepatocytes (60 kDa) and platelets (50 kDa), with MW differences attributable to glycosylation. CPB2 is cleaved by thrombin and plasmin, generating a 36 kDa, relatively insoluble nonglycosylated enzymatically active fragment (TAFIa).

Concentration: 0.8mg/ml

Immunogen: Recombinant Human CPB2 protein expressed by E.coli.

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH 7.4

Purification Method: Antigen Affinity Purification

Dilution: WB 1:250-1:500

Calculated MW: 48 kDa

Observed MW: 56 kDa

Storage: -20°C/One year. Avoid freeze / thaw cycles.

Shipping: Ice bag

Research Use Only