CASP8AP2 Rabbit pAb
Sizes: 20μL, 100μL
Catalogue Numbers: A15770-20, A15770-100
Citations, Manuals and MSDS Available upon request.
Background: This protein is highly similar to FLASH, a mouse apoptotic protein identified by its interaction with the death-effector domain (DED) of caspase 8. Studies of FLASH protein suggested that this protein may be a component of the death-inducing signaling complex that includes Fas receptor, Fas-binding adapter FADD, and caspase 8, and plays a regulatory role in Fas-mediated apoptosis. Alternative splicing results in multiple transcript variants encoding the same protein.
Category: Polyclonal Antibodies
Applications: WB, ELISA
Cross-reactivity: Human
Protein Weight: 223kDa
Observed Molecular Weight: 215kDa
Immunogen: Recombinant protein (or fragment)
Species: Human
GeneID: 9994
SWISS: Q9UKL3
Alternate Names: CED-4; FLASH; RIP25; CASP8AP2
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.01% thimerosal, 50% glycerol, pH 7.3.
Recommended Dilutions: WB, 1:500 - 1:2000 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Research Areas: Cell Biology Developmental Biology, Apoptosis.
NCBI Alias: CASP8AP2
Research Use Only