CaVα2δ1 rabbit pAb - ES20793

CaVα2δ1 rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES20793-50, ES20793-100

Citations, Manuals and MSDS Available upon request.

Background: calcium voltage-gated channel auxiliary subunit alpha2delta 1 (CACNA2D1) Homo sapiens The preproprotein encoded by this gene is cleaved into multiple chains that comprise the alpha-2 and delta subunits of the voltage-dependent calcium channel complex. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization. Mutations in this gene can cause cardiac deficiencies, including Brugada syndrome and short QT syndrome. Alternate splicing results in multiple transcript variants, some of which may lack the delta subunit portion. [provided by RefSeq, Nov 2014],

Alternate Name: Voltage-dependent calcium channel subunit alpha-2/delta-1 (Voltage-gated calcium channel subunit alpha-2/delta-1) [Cleaved into: Voltage-dependent calcium channel subunit alpha-2-1; Voltage-dependent calcium channel subunit delta-1]

Source: Rabbit

Applications: WB; IHC; IF

Dilution: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.

Reactivity: Rat

Immunogen: Synthetic Peptide of CaVα2δ1

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Observed Band (KD): 100-130kD

Human Gene ID: 781

Human SWISS Prot NO: P54289

Subcellular Location: Membrane; Single-pass type I membrane protein.

Research Use Only