CD141/Thrombomodulin Rabbit PolymAb®
Sizes: 20μL, 100μL
Catalogue Numbers: A22989PM-20, A22989PM-100
Citations, Manuals and MSDS Available upon request.
Background: The protein encoded by this intronless gene is an endothelial-specific type I membrane receptor that binds thrombin. This binding results in the activation of protein C, which degrades clotting factors Va and VIIIa and reduces the amount of thrombin generated. Mutations in this gene are a cause of thromboembolic disease, also known as inherited thrombophilia.
Category: Monoclonal Antibodies
Applications: WB, IHC-P, IF/ICC, FC, ELISA
Cross-reactivity: Human
Protein Weight: 60kDa
Observed Molecular Weight: 90kDa
Immunogen: Recombinant protein (or fragment) .
Species: Human
GeneID: 7056
SWISS: P07204
Alternate Names: TM; THRM; AHUS6; BDCA3; CD141; BDCA-3; THPH12
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol and 0.05% BSA, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
Recommended Dilutions: WB, 1:2000 - 1:10000 IHC-P, 1:100 - 1:500 IF/ICC, 1:50 - 1:200 FC, 1:500 - 1:1000 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Research Areas: Immunology Inflammation, CDs, Stem Cells, Cardiovascular, Blood.
NCBI Alias: THBD
Research Use Only