Product Description

CD272 Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS61756-50, BS61756-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: B and T lymphocyte attenuator (BTLA) is an immunoglobμlin domain-containing glycoprotein whose expression is induced during T-cell activation. BTLA is similar to CTLA-4 and PD-1, all of which are coinhibitory receptors belonging to the CD28 family. However, unlike CTLA-4 and PD-1, BTLA does not interact with B7-Ig family counter receptors. Rather, the herpesvirus entry mediator (HVEM), a TNF receptor, acts as a molecμlar switch that modμlates T-cell activation by propagating inhibitory signals through BTLA. The BTLAHVEM interaction is conserved between mouse and human, suggesting that this system is an important pathway regμlating lymphocyte activation

Category: Primary Antibody

Reactivity: Human, Mouse, Rat

Host: Rabbit

Applications: WB

Alternate Names: B- and T-lymphocyte attenuator, B- and T-lymphocyte-associated protein, CD272, BTLA

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: Synthetic peptide, corresponding to amino acids 130-180 of Human BTLA.

Dilution: WB: 1:500~1:1000

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: CD272 polyclonal antibody detects endogenous levels of CD272 protein.

Molecular Weight: ~ 32 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: Q7Z6A9

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Research Use Only