Product Description

CD284 Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA20608-50, RA20608-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: toll like receptor 4 (TLR4) Homo sapiens The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This receptor has been implicated in signal transduction events induced by lipopolysaccharide (LPS) found in most gram-negative bacteria. Mutations in this gene have been associated with differences in LPS responsiveness. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012],

Reactivity: Human, Mouse

Host: Rabbit

Applications: IF/ICC, WB, IHC-p, ELISA

Alternate Names: TLR4, Toll-like receptor 4, hToll, CD antigen CD284

Clonality: Polyclonal

Dilution: IF: 1:50-200 Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.

Molecular Weight: 95

Protein Molecular Weight (kDa): 95

Storage: -20°C/1 year

Human Gene ID: 7099

Human SwissProt Number: O00206

Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Research Use Only