Product Description

CD2BP2 Rabbit Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: ES1904-50, ES1904-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: This gene encodes a bi-functional protein. In the cytoplasm, the encoded protein binds the cytoplasmic tail of human surface antigen CD2 via its C-terminal GYF domain, and regulate CD2-triggered T lymphocyte activation. In the nucleus, this protein is a component of the U5 small nuclear ribonucleoprotein complex and is involved in RNA splicing. A pseudogene has been identified on chromosome 7. Alternative splicing results in multiple transcript variants but their biological validity has not been determined. [provided by RefSeq, Nov 2008],

Reactivity: Human, Monkey

Host: Rabbit

Applications: WB, IHC, IF, ELISA

Alternate Names: CD2BP2, KIAA1178, CD2 antigen cytoplasmic tail-binding protein 2, CD2 cytoplasmic domain-binding protein 2, CD2 tail-binding protein 2

Clonality: Polyclonal

Immunogen: The antiserum was produced against synthesized peptide derived from human CD2 Tail-binding. AA range:101-150

Isotype: IgG

Target: CD2BP2

Specificity: CD2BP2 Polyclonal Antibody detects endogenous levels of CD2BP2 protein.

Dilution: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration: 1 mg/ml,

Formlation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Expression: Aorta, Brain, Epithelium, Liver, Lung,

Observed Band (KD): 50kD

Function: Similarity: Contains 1 GYF domain
Subunit: Binds the cytoplasmic domain of CD2 through the GYF domain

Subcellular Location: Cytoplasm Nucleus Predominantly nuclear

Storage and Stability: -20°C/1 year

Gene Name: CD2BP2

Protein Name: CD2 antigen cytoplasmic tail-binding protein 2

Mouse SwissProt Number: Q9CWK3

Research Use Only