Product Description

CD4 Recombinant Rabbit mAb

Sizes: 50μl, 100μl

Catalogue Numbers: BS46075-50, BS46075-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: Integral membrane glycoprotein that plays an essential role in the immune response and serves mμltiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecμle:peptide complex. The antigens presented by class II peptides are derived from extracellμlar proteins while class I peptides are derived from cytosolic proteins. Interacts simμltaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kinase LCK to the vicinity of the TCR-CD3 complex. LCK then initiates different intracellμlar signaling pathways by phosphorylating various substratesμltimately leading to lymphokine production, motility, adhesion and activation of T-helper cells.

Category: Primary Antibody

Reactivity: Mouse

Host: Rabbit

Applications: WB, IHC, IP

Alternate Names: L3T4, Ly-4

Clonality: Monoclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: Recombinant protein of mouse CD4

Dilution: WB: 1:1000 IHC: 1:200-1:1000 IP: 1:20

Purification: Affinity Purification

Specificity: IgG

Molecular Weight: 51 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: P06332

Product: Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

Research Use Only