Product Description

CD83 Rabbit Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: ES1917-50, ES1917-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: The protein encoded by this gene is a single-pass type I membrane protein and member of the immunoglobulin superfamily of receptors. The encoded protein may be involved in the regulation of antigen presentation. A soluble form of this protein can bind to dendritic cells and inhibit their maturation. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011],

Reactivity: Human, Rat, Mouse,

Host: Rabbit

Applications: WB, IHC, IF, ELISA

Alternate Names: CD83, CD83 antigen, hCD83, B-cell activation protein, Cell surface protein HB15, CD antigen CD83

Clonality: Polyclonal

Immunogen: The antiserum was produced against synthesized peptide derived from human CD83. AA range:101-150

Isotype: IgG

Target: CD83

Specificity: CD83 Polyclonal Antibody detects endogenous levels of CD83 protein.

Dilution: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration: 1 mg/ml,

Formlation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Expression: Expressed by activated lymphocytes, Langerhans cells and interdigitating reticulum cells,

Observed Band (KD): 23kD

Function: Function: May play a significant role in antigen presentation or the cellular interactions that follow lymphocyte activation
Online Information: CD83 antigen,Similarity: Contains 1 Ig-like V-type (immunoglobulin-like) domain
Subunit: Monomer
Tissue Specificity: Expressed by activated lymphocytes, Langerhans cells and interdigitating reticulum cells

Subcellular Location: Membrane, Single-pass type I membrane protein

Storage and Stability: -20°C/1 year

Gene Name: CD83

Protein Name: CD83 antigen

Mouse SwissProt Number: O88324

Research Use Only