Product Description

CDC46 Rabbit Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: ES1933-50, ES1933-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: The protein encoded by this gene is structurally very similar to the CDC46 protein from S. cerevisiae, a protein involved in the initiation of DNA replication. The encoded protein is a member of the MCM family of chromatin-binding proteins and can interact with at least two other members of this family. The encoded protein is upregulated in the transition from the G0 to G1/S phase of the cell cycle and may actively participate in cell cycle regulation. [provided by RefSeq, Jul 2008],

Reactivity: Human, Mouse, Rat

Host: Rabbit

Applications: WB, IHC, IF, ELISA

Alternate Names: MCM5, CDC46, DNA replication licensing factor MCM5, CDC46 homolog, P1-CDC46

Clonality: Polyclonal

Immunogen: The antiserum was produced against synthesized peptide derived from human MCM5. AA range:21-70

Isotype: IgG

Target: CDC46

Specificity: CDC46 Polyclonal Antibody detects endogenous levels of CDC46 protein.

Dilution: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration: 1 mg/ml,

Formlation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Expression: Cervix, Cervix carcinoma, Lymph, Placenta, Spleen, Thymus, Tongue

Observed Band (KD): 90kD

Fields: DNA replication, Cell cycle

Function: Similarity: Belongs to the MCM family
Similarity: Contains 1 MCM domain

Subcellular Location: Nucleus Chromosome Cytoplasm, cytosol Associated with chromatin before the formation of nuclei and detaches from it as DNA replication progresses

Storage and Stability: -20°C/1 year

Gene Name: MCM5

Protein Name: DNA replication licensing factor MCM5

Mouse SwissProt Number: P49718

Research Use Only