Product Description

Cdc6 Recombinant Rabbit mAb

Sizes: 50μl, 100μl

Catalogue Numbers: BS45112-50, BS45112-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: The protein encoded by this gene is highly similar to Saccharomyces cerevisiae Cdc6, a protein essential for the initiation of DNA replication. This protein functions as a regμlator at the early steps of DNA replication. It localizes in cell nucleus during cell cyle G1, but translocates to the cytoplasm at the start of S phase. The subcellμlar translocation of this protein during cell cyle is regμlated through its phosphorylation by Cdks. Transcription of this protein was reported to be regμlated in response to mitogenic signals through transcriptional control mechanism involving E2F proteins. [provided by RefSeq, Jμl 2008]

Category: Primary Antibody

Reactivity: Human

Host: Rabbit

Applications: WB, IHC, ICC/IF

Alternate Names: CDC18L, HsCDC6, MGORS5, HsCDC18

Clonality: Monoclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: A synthetic peptide of human Cdc6

Dilution: WB: 1:1000-1:5000 IHC: 1:50-1:100 ICC/IF: 1:50-1:100

Purification: Affinity Purification

Specificity: IgG

Molecular Weight: 63 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: Q99741

Product: Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

Research Use Only