Product Description

CDH22 Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS61569-50, BS61569-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: The cadherins are a family of Ca2+-dependent adhesion molecμles that function to mediate cell-cell binding critical to the maintenance of structure and morphogenesis. Cadherins each contain a large extracellμlar domain at the N-terminus, which is characterized by a series of five homologous repeats, the most distal of which is thought to be responsible for binding specificity. Cadherin-22, also known as CDH22 or PB-cadherin (pituitary and brain cadherin), is an 828 amino acid single-pass type I membrane protein that, characteristic of cadherin proteins, contains five cadherin domains. Expressed predominately in brain, cadherin-22 functions as a Ca2+-dependent cell adhesion protein that is thought to play an important role in tissue formation and morphogenesis, specifically in neural cells during the development and maintenance of brain tissue.

Category: Primary Antibody

Reactivity: Human

Host: Rabbit

Applications: WB

Alternate Names: Cadherin-22, Pituitary and brain cadherin, PB-cadherin

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: Synthetic peptide, corresponding to amino acids 119-163 of Human CDH22

Dilution: WB: 1:500~1:1000

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE)

Specificity: CDH22 polyclonal antibody detects endogenous levels of CDH22 protein.

Molecular Weight: ~ 89 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: Q9UJ99

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Research Use Only