Product Description

CDX-2 Monoclonal Antibody

Sizes: 100μL, 200μL

Catalogue Numbers: PA6305R-100, PA6305R-200

Citations, Manuals and MSDS Available upon request.

Abbreviation: CDX-2

Target Synonym: Caudal type homeo box 2, Caudal type homeo box transcription factor 2, Caudal type homeobox 2, Caudal type homeobox protein 2, Caudal type homeobox transcription factor 2, Caudal-type homeobox protein 2, CDX 2, CDX 3, CDX-3, Cdx2, CDX2/AS, CDX2, CDX3, Homeobox protein CDX 2, Homeobox protein CDX-2

Conjugation: Unconjugated

Host: Rabbit

Species Reactivity: Human

Application: IHC-P

Clonality: Monoclonal

Clone No.: YN00475r

UNIProt ID: Q99626

Background: CDX2 is a kind of intestinal specific transcription factor, which is expressed in the early stage of intestinal development, participates in regulating the proliferation and differentiation of intestinal epithelial cells, and locates on the villi and crypt surface of intestinal epithelium. In the gut (from duodenum to rectum), CDX2 nucleoprotein is strongly and evenly expressed in all types of epithelial cells. In tumor tissue, CDX2 is expressed in most colorectal adenocarcinoma and appendiceal adenocarcinoma. CDX2 is a relatively sensitive and specific marker of intestinal adenocarcinoma. CDX2 deficiency can promote the development of sporadic colon cancer, and it is also a significant feature of low differentiation colorectal cancer.

The concentrated should be stored at -20°C protecting from light,The RTU should be stored at 2~8°C protecting from light (Do not freeze).Valid for 12 months.

Shipping: Ice bag

Research Use Only