Product Description

CDY2 Rabbit Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: ES17538-50, ES17538-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: This intronless gene encodes a protein containing a chromodomain and a histone acetyltransferase catalytic domain. Chromodomain proteins are components of heterochromatin-like complexes and can act as gene repressors. This protein is localized to the nucleus of late spermatids where histone hyperacetylation takes place. Histone hyperacetylation is thought to facilitate the transition in which protamines replace histones as the major DNA-packaging protein. Two nearly identical copies of this gene are found in a palindromic region on chromosome Y, this record represents the telomeric copy. Chromosome Y also contains a pair of closely related genes in another more telomeric palindrome as well as several related pseudogenes. [provided by RefSeq, Jul 2008],

Reactivity: Human, Rat, Mouse,

Host: Rabbit

Applications: WB

Clonality: Polyclonal

Immunogen: Synthesized peptide derived from human CDY2 AA range: 434-484

Isotype: IgG

Target: CDY2

Specificity: This antibody detects endogenous levels of CDY2 at Human

Dilution: WB 1：500-2000

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

Concentration: 1 mg/ml,

Formlation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Expression: Testis specific,

Molecular Weight (Da): 60kD

Function: Catalytic Activity: Acetyl-CoA + histone = CoA + acetylhistone
Function: May have histone acetyltransferase activity
Similarity: Contains 1 chromo domain
Tissue Specificity: Testis specific

Subcellular Location: Nucleus

Storage and Stability: -20°C/1 year

Gene Name: CDY2A CDY2, CDY2B

Protein Name: CDY2

Research Use Only