Product Description

CE120 Rabbit Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: ES17529-50, ES17529-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: This gene encodes a protein that functions in the microtubule-dependent coupling of the nucleus and the centrosome. A similar protein in mouse plays a role in both interkinetic nuclear migration, which is a characteristic pattern of nuclear movement in neural progenitors, and in neural progenitor self-renewal. Mutations in this gene are predicted to result in neurogenic defects. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009],

Reactivity: Human, Mouse

Host: Rabbit

Applications: WB

Clonality: Polyclonal

Immunogen: Synthesized peptide derived from human CE120 AA range: 335-385

Isotype: IgG

Target: CE120

Specificity: This antibody detects endogenous levels of CE120 at Human/Mouse

Dilution: WB 1：500-2000

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

Concentration: 1 mg/ml,

Formlation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Molecular Weight (Da): 108kD

Function: Function: Plays a role in the microtubule-dependent coupling of the nucleus and the centrosome. Involved in the processes that regulate centrosome-mediated interkinetic nuclear migration (INM) of neural progenitors and for proper positioning of neurons during brain development. Also implicated in the migration and selfrenewal of neural progenitors
Similarity: Belongs to the CEP120 family
Subcellular Location: Regulates the localization of TACC3 to the centrosome in neural progenitors in vivo
Subunit: Interacts with TACC2 and TACC3

Subcellular Location: Cytoplasm, cytoskeleton, microtubule organizing center, centrosome Regulates the localization of TACC3 to the centrosome in neural progenitors in vivo

Storage and Stability: -20°C/1 year

Gene Name: CEP120 CCDC100

Protein Name: CE120

Mouse Gene ID: 225523

Mouse SwissProt Number: Q7TSG1

Research Use Only