Product Description

CEL3B Rabbit Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: ES17526-50, ES17526-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: Elastases form a subfamily of serine proteases that hydrolyze many proteins in addition to elastin. Humans have six elastase genes which encode the structurally similar proteins elastase 1, 2, 2A, 2B, 3A, and 3B. Unlike other elastases, elastase 3B has little elastolytic activity. Like most of the human elastases, elastase 3B is secreted from the pancreas as a zymogen and, like other serine proteases such as trypsin, chymotrypsin and kallikrein, it has a digestive function in the intestine. Elastase 3B preferentially cleaves proteins after alanine residues. Elastase 3B may also function in the intestinal transport and metabolism of cholesterol. Both elastase 3A and elastase 3B have been referred to as protease E and as elastase 1, and excretion of this protein in fecal material is frequently used as a measure of pancreatic function in clinical assays. [provided by RefSeq, May 2009],

Reactivity: Human, Mouse

Host: Rabbit

Applications: WB

Clonality: Polyclonal

Immunogen: Synthesized peptide derived from human CEL3B AA range: 206-256

Isotype: IgG

Target: CEL3B

Specificity: This antibody detects endogenous levels of CEL3B at Human/Mouse

Dilution: WB 1：500-2000

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

Concentration: 1 mg/ml,

Formlation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Expression: Pancreas, Not detectable in keratinocytes,

Molecular Weight (Da): 30kD

Fields: Pancreatic secretion, Protein digestion and absorption

Subcellular Location: extracellular space,

Storage and Stability: -20°C/1 year

Gene Name: CELA3B ELA3B

Protein Name: CEL3B

Mouse Gene ID: 67868

Mouse SwissProt Number: Q9CQ52

Research Use Only