Product Description

CEP170 Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS61661-50, BS61661-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: Centrosomal protein 170kDa, also known as CEP170, is a protein that in humans is encoded by the CEP170 geneThe product of this gene is a component of the centrosome, a non-membraneous organelle that functions as the major microtubμle-organizing center in animal cells. During interphase, the encoded protein localizes to the sub-distal appendages of mature centrioles, which are microtubμle-based structures thought to help organize centrosomes. During mitosis, the protein associates with spindle microtubμles near the centrosomes. The protein interacts with the intraflagellar transport protein 81 (IFT81), the SH3-domain containing protein PRAX-1, and is phosphorylated by cyclin dependent kinase 1 (Cdk1) and polo-like kinase 1 (PLK1), and functions in maintaining Microtubμle organization, cell morphology and cilium stability.

Category: Primary Antibody

Reactivity: Human

Host: Rabbit

Applications: WB

Alternate Names: Centrosomal protein of 170 kDa, Cep170, KARP-1-binding protein, KARP1-binding protein, CEP170, FAM68A, KAB, KIAA0470

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: Synthetic peptide, corresponding Human CEP170.

Dilution: WB: 1:500~1:1000

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: CEP170 polyclonal antibody detects endogenous levels of CEP170 protein.

Molecular Weight: ~ 175 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: Q5SW79

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Research Use Only