Product Description

CEP85 Rabbit Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: ES17522-50, ES17522-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: This gene encodes a protein that belongs to the centrosome-associated family of proteins. The centrosome is a subcellular organelle in the animal cell that functions as a microtubule organizing center and is involved in cell-cycle progression. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013],

Reactivity: Human, Mouse

Host: Rabbit

Applications: WB

Alternate Names: Centrosomal protein of 85 kDa (Coiled-coil domain-containing protein 21)

Clonality: Polyclonal

Immunogen: Synthesized peptide derived from human CEP85 AA range: 267-317

Isotype: IgG

Target: CEP85

Specificity: This antibody detects endogenous levels of CEP85 at Human/Mouse

Dilution: WB 1:500-2000

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

Concentration: 1 mg/ml,

Formlation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.295% sodium azide.

Expression: Hepatoma, Placenta, Retinoblastoma, Testis,

Observed Band (KD): 85kD

Function: Similarity: Belongs to the CCDC21 family

Subcellular Location: Cytoplasm, cytoskeleton, microtubule organizing center, centrosome Cytoplasm, cytoskeleton, spindle pole Nucleus, nucleolus Localizes to centrosomes and nucleolus in interphase Upon entry into mitosis, relocates from nucleolus and accumulates at spindle poles (PubMed:21399614) Associated with the pericentriolar material Localizes to centrosomes at a low level in G1 phase and a slightly increased level in S phase, with gradually elevated levels during G2 phase The levels at centrosomes further increase at G2/M, reaching a peak at spindle poles at early mitotic stages and remain high until the end of anaphase (PubMed:26220856)

Storage and Stability: -20°C/1 year

Gene Name: CEP85 CCDC21

Protein Name: CEP85

Mouse Gene ID: 70012

Mouse SwissProt Number: Q8BMK0

Research Use Only