Product Description

CETN2 Rabbit Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: ES17517-50, ES17517-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: Caltractin belongs to a family of calcium-binding proteins and is a structural component of the centrosome. The high level of conservation from algae to humans and its association with the centrosome suggested that caltractin plays a fundamental role in the structure and function of the microtubule-organizing center, possibly required for the proper duplication and segregation of the centrosome. [provided by RefSeq, Jul 2008],

Reactivity: Human, Mouse

Host: Rabbit

Applications: WB

Clonality: Polyclonal

Immunogen: Synthesized peptide derived from human CETN2 AA range: 1-51

Isotype: IgG

Target: CETN2

Specificity: This antibody detects endogenous levels of CETN2 at Human/Mouse

Dilution: WB 1：500-2000

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

Concentration: 1 mg/ml,

Formlation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Molecular Weight (Da): 19kD

Fields: Nucleotide excision repair

Function: Function: Plays a fundamental role in microtubule-organizing center structure and function. Required for centriole duplication and correct spindle formation. Has a role in regulating cytokinesis and genome stability via cooperation with CALM1 and CEP110
Miscellaneous: Binds two moles of calcium per mole of protein
Similarity: Belongs to the centrin family
Similarity: Contains 4 EF-hand domains
Subcellular Location: Centrosome of S-phase, interphase and mitotic cells
Subunit: Monomer. Interacts with CEP110, SFI1 and with XPC

Subcellular Location: Cytoplasm, cytoskeleton, microtubule organizing center, centrosome Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole Nucleus envelope Nucleus, nuclear pore complex Nucleus

Storage and Stability: -20°C/1 year

Gene Name: CETN2 CALT CEN2

Protein Name: CETN2

Mouse Gene ID: 26370

Mouse SwissProt Number: Q9R1K9

Research Use Only