Chek2 Rabbit pAb
Sizes: 20μL, 100μL
Catalogue Numbers: A23664-20, A23664-100
Citations, Manuals and MSDS Available upon request.
Background: Enables protein kinase activity. Acts upstream of or within cellular response to gamma radiation; peptidyl-serine phosphorylation; and signal transduction by p53 class mediator. Predicted to be located in Golgi apparatus and PML body. Predicted to be active in cytoplasm and nucleus. Predicted to colocalize with chromosome, telomeric region. Is expressed in several structures, including central nervous system; genitourinary system; and liver. Human ortholog (s) of this gene implicated in several diseases, including Li-Fraumeni syndrome 2; breast cancer (multiple) ; colorectal cancer; osteosarcoma; and prostate cancer. Orthologous to human CHEK2 (checkpoint kinase 2).
Category: Polyclonal Antibodies
Applications: WB, ELISA
Cross-reactivity: Human, Mouse
Protein Weight: 61kDa
Observed Molecular Weight: 62-68kDa
Immunogen: Recombinant protein (or fragment)
Species: Human
GeneID: 50883
SWISS: Q9Z265
Alternate Names: CHK2; Cds1; Rad53; HUCDS1; Chek2
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
Recommended Dilutions: WB, 1:1000 - 1:5000 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
NCBI Alias: Chek2
Research Use Only