Product Description

CHIC2 Rabbit Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: ES17481-50, ES17481-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: This gene encodes a member of the CHIC family of proteins. The encoded protein contains a cysteine-rich hydrophobic (CHIC) motif, and is localized to vesicular structures and the plasma membrane. This gene is associated with some cases of acute myeloid leukemia. [provided by RefSeq, Jul 2008],

Reactivity: Human, Mouse

Host: Rabbit

Applications: WB

Clonality: Polyclonal

Immunogen: Synthesized peptide derived from human CHIC2 AA range: 111-161

Isotype: IgG

Target: CHIC2

Specificity: This antibody detects endogenous levels of CHIC2 at Human/Mouse

Dilution: WB 1：500-2000

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

Concentration: 1 mg/ml,

Formlation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Molecular Weight (Da): 18kD

Function: Disease: A chromosomal aberration involving CHIC2 is found in a form of acute myeloid leukemia (AML). Translocation t(4, 12)(q12, p13) with ETV6
PTM: Palmitoylation in the CHIC motif is required for membrane association
Similarity: Belongs to the CHIC family
Subcellular Location: Also present at a Golgi-like vesicular compartment and at scattered vesicles

Subcellular Location: Cell membrane Cytoplasmic vesicle Also present at a Golgi-like vesicular compartment and at scattered vesicles

Storage and Stability: -20°C/1 year

Gene Name: CHIC2 BTL

Protein Name: CHIC2

Mouse Gene ID: 74277

Mouse SwissProt Number: Q9D9G3

Research Use Only