Product Description

CHP3 Rabbit Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: ES17472-50, ES17472-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Reactivity: Human, Mouse

Host: Rabbit

Applications: WB

Clonality: Polyclonal

Immunogen: Synthesized peptide derived from human CHP3 AA range: 20-70

Isotype: IgG

Target: CHP3

Specificity: This antibody detects endogenous levels of CHP3 at Human/Mouse

Dilution: WB 1：500-2000

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

Concentration: 1 mg/ml,

Formlation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Expression: Expressed in mature megakaryocytes and polymorphonuclear granulocytes (at protein level), Abundantly expressed in heart, Also expressed at a lower level in adult testis and salivary gland, and in the placenta,

Molecular Weight (Da): 24kD

Function: Caution: It is uncertain whether Met-1 or Met-54 is the initiator
Cofactor: Binds calcium
Developmental Stage: Strongly up-regulated in K562 cells treated by PMA to promote megakaryocytic differentiation, but not when treated by DMSO to promote granulocytic differentiation or by hemin to promote erythroid differentiation (at protein level)
Function: Essential for the coupling of ERK cascade activation with the expression of ETS family genes in megakaryocytic differentiation
Similarity: Contains 1 EF-hand domain
Subunit: Interacts with Sodium/hydrogen exchanger 1 (SLC9A1)
Tissue Specificity: Abundantly expressed in heart

Subcellular Location: Nucleus Cytoplasm Membrane, Lipid-anchor Cell membrane Cell projection, lamellipodium Cell projection, ruffle membrane Colocalizes with SLC9A1 at the plasma membrane

Storage and Stability: -20°C/1 year

Gene Name: TESC CHP3

Protein Name: CHP3

Mouse Gene ID: 57816

Mouse SwissProt Number: Q9JKL5

Research Use Only