Product Description

CHST7 Rabbit Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: ES17463-50, ES17463-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: This gene is a member of the Gal/GalNAc/GlcNAc (galactose/N-acetylgalactosamine/N-acetylglucosamine) 6-O-sulfotransferase (GST) family. Members of this family encode enzymes that catalyze the specific addition of sulfate groups to distinct hydroxyl and amino groups of carbohydrates. The encoded protein catalyzes the sulfation of 6-hydroxyl group of GalNAc in chondroitin. [provided by RefSeq, Aug 2013],

Reactivity: Human, Mouse, Rat

Host: Rabbit

Applications: WB

Clonality: Polyclonal

Immunogen: Synthesized peptide derived from human CHST7 AA range: 299-349

Isotype: IgG

Target: CHST7

Specificity: This antibody detects endogenous levels of CHST7 at Human/Mouse/Rat

Dilution: WB 1：500-2000

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

Concentration: 1 mg/ml,

Formlation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Expression: Widely expressed, Highly expressed in heart, spleen, liver and ovary, Expressed at lower level in brain, placenta, thyroid, spinal cord and peripheral blood leukocytes, Not expressed in adult skin,

Molecular Weight (Da): 53kD

Fields: Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate

Function: Catalytic Activity: 3'-phosphoadenylyl sulfate + chondroitin = adenosine 3',5'-bisphosphate + chondroitin 6'-sulfate
Function: Catalyzes the transfer of sulfate to position 6 of non-reducing N-acetylglucosamine (GlcNAc) residues. Preferentially acts on mannose-linked GlcNAc. Also able to catalyze the transfer of sulfate to position 6 of the N-acetylgalactosamine (GalNAc) residue of chondroitin. Also acts on core 2 mucin-type oligosaccharide and N-acetyllactosamine oligomer with a lower efficiency. Has weak or no activity toward keratan sulfate and oligosaccharides containing the Galbeta1-4GlcNAc. Catalyzes 6-O-sulfation of beta-benzyl GlcNAc but not alpha- or beta-benzyl GalNAc
Online Information: GlycoGene database,Similarity: Belongs to the sulfotransferase 1 family. Gal/GlcNAc/GalNAc subfamily
Tissue Specificity: Widely expressed. Highly expressed in heart, spleen, liver and ovary. Expr

Subcellular Location: Golgi apparatus membrane, Single-pass type II membrane protein

Storage and Stability: -20°C/1 year

Gene Name: CHST7

Protein Name: CHST7

Mouse Gene ID: 60322

Mouse SwissProt Number: Q9EP78

Rat Gene ID: 302302

Rat SwissProt Number: Q6XQG8

Research Use Only