Product Description

Cks1 Rabbit Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: ES1984-50, ES1984-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: CKS1B protein binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. The CKS1B mRNA is found to be expressed in different patterns through the cell cycle in HeLa cells, which reflects a specialized role for the encoded protein. At least two transcript variants have been identified for this gene, and it appears that only one of them encodes a protein. [provided by RefSeq, Sep 2008],

Reactivity: Human, Mouse

Host: Rabbit

Applications: WB, IF, ELISA

Alternate Names: CKS1B, CKS1, PNAS-143, PNAS-16, Cyclin-dependent kinases regulatory subunit 1, CKS-1

Clonality: Polyclonal

Immunogen: The antiserum was produced against synthesized peptide derived from human CKS1. AA range:10-59

Isotype: IgG

Target: Cks1

Specificity: Cks1 Polyclonal Antibody detects endogenous levels of Cks1 protein.

Dilution: Western Blot: 1/500 - 1/2000. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration: 1 mg/ml,

Formlation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Expression: Brain, Muscle, Promyelocytic leukemia, Prostate, Tongue,

Observed Band (KD): 9kD

Fields: Pathways in cancer, Small cell lung cancer

Function: Function: Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function
Similarity: Belongs to the CKS family
Subunit: Forms a homohexamer that can probably bind six kinase subunits

Subcellular Location: cyclin-dependent protein kinase holoenzyme complex, nucleoplasm, SCF ubiquitin ligase complex,

Storage and Stability: -20°C/1 year

Gene Name: CKS1B

Protein Name: Cyclin-dependent kinases regulatory subunit 1

Mouse Gene ID: 54124

Mouse SwissProt Number: P61025

Research Use Only