Product Description

CL16A Rabbit Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: ES17408-50, ES17408-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: This gene encodes a member of the C-type lectin domain containing family. Single nucleotide polymorphisms in introns of this gene have been associated with diabetes mellitus, multiple sclerosis and rheumatoid arthritis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2011],

Reactivity: Human, Mouse

Host: Rabbit

Applications: WB

Clonality: Polyclonal

Immunogen: Synthesized peptide derived from human CL16A AA range: 129-179

Isotype: IgG

Target: CL16A

Specificity: This antibody detects endogenous levels of CL16A at Human/Mouse

Dilution: WB 1：500-2000

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

Concentration: 1 mg/ml,

Formlation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Expression: Almost exclusively expressed in immune cells, including dendritic cells, B-lymphocytes and natural killer cells,

Molecular Weight (Da): 116kD

Function: Disease: Defects in CLEC16A might be a cause of insulin-dependent diabetes mellitus (IDDM) [MIM: 222100]
Similarity: Belongs to the CLEC16A/gop-1 family
Tissue Specificity: Almost exclusively expressed in immune cells, including dendritic cells, B lymphocytes and natural killer cells

Subcellular Location: Endosome membrane, Peripheral membrane protein Lysosome membrane, Peripheral membrane protein Associates with the endolysosome membrane

Storage and Stability: -20°C/1 year

Gene Name: CLEC16A KIAA0350

Protein Name: CL16A

Mouse Gene ID: 74374

Mouse SwissProt Number: Q80U30

Research Use Only