Product Description

CLC4E Rabbit Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: ES17384-50, ES17384-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: This gene encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. Members of this family share a common protein fold and have diverse functions, such as cell adhesion, cell-cell signalling, glycoprotein turnover, and roles in inflammation and immune response. The encoded type II transmembrane protein is a downstream target of CCAAT/enhancer binding protein (C/EBP), beta (CEBPB) and may play a role in inflammation. Alternative splice variants have been described but their full-length sequence has not been determined. This gene is closely linked to other CTL/CTLD superfamily members on chromosome 12p13 in the natural killer gene complex region. [provided by RefSeq, Jul 2008],

Reactivity: Human, Mouse, Rat

Host: Rabbit

Applications: WB

Clonality: Polyclonal

Immunogen: Synthesized peptide derived from human CLC4E AA range: 46-96

Isotype: IgG

Target: CLC4E

Specificity: This antibody detects endogenous levels of CLC4E at Human/Mouse/Rat

Dilution: WB 1：500-2000

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

Concentration: 1 mg/ml,

Formlation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Expression: Expressed in monocytes and macrophages,

Molecular Weight (Da): 24kD

Fields: C-type lectin receptor signaling pathway, Tuberculosis

Function: Function: May play a role in the response to inflammatory stimuli in peritoneal macrophages. May be involved in immune surveillance processes under transcriptional control of CEBPB
Online Information: Mincle,Similarity: Contains 1 C-type lectin domain

Subcellular Location: Cell membrane, Single-pass type II membrane protein Cell projection, phagocytic cup

Storage and Stability: -20°C/1 year

Gene Name: CLEC4E CLECSF9 MINCLE UNQ218/PRO244

Protein Name: CLC4E

Mouse Gene ID: 56619

Mouse SwissProt Number: Q9R0Q8

Rat Gene ID: 450223

Rat SwissProt Number: Q67EQ1

Research Use Only