Product Description

CLCB Rabbit Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: ES17382-50, ES17382-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: Clathrin is a large, soluble protein composed of heavy and light chains. It functions as the main structural component of the lattice-type cytoplasmic face of coated pits and vesicles which entrap specific macromolecules during receptor-mediated endocytosis. This gene encodes one of two clathrin light chain proteins which are believed to function as regulatory elements. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2008],

Reactivity: Human, Mouse, Rat

Host: Rabbit

Applications: WB

Clonality: Polyclonal

Immunogen: Synthesized peptide derived from human CLCB AA range: 168-218

Isotype: IgG

Target: CLCB

Specificity: This antibody detects endogenous levels of CLCB at Human/Mouse/Rat

Dilution: WB 1：500-2000

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

Concentration: 1 mg/ml,

Formlation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Molecular Weight (Da): 25kD

Fields: Lysosome, Endocytosis, Synaptic vesicle cycle, Endocrine and other factor-regulated calcium reabsorption, Huntington disease, Bacterial invasion of epithelial cells

Function: Function: Clathrin is the major protein of the polyhedral coat of coated pits and vesicles
Subcellular Location: Cytoplasmic face of coated pits and vesicles
Subunit: Clathrin coats are formed from molecules containing 3 heavy chains and 3 light chains. Interacts (via N-terminus) with HIP1. Interacts with HIP1R

Subcellular Location: Cytoplasmic vesicle membrane, Peripheral membrane protein, Cytoplasmic side Membrane, coated pit, Peripheral membrane protein, Cytoplasmic side Cytoplasmic face of coated pits and vesicles

Storage and Stability: -20°C/1 year

Gene Name: CLTB

Protein Name: CLCB

Mouse Gene ID: 74325

Mouse SwissProt Number: Q6IRU5

Rat Gene ID: 116561

Rat SwissProt Number: P08082

Research Use Only