CLN1 Polyclonal Antibody - BT-AP01985

CLN1 Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP01985-20, BT-AP01985-50, BT-AP01985-100

Citations, Manuals and MSDS Available upon request.

Background: The protein encoded by PPT1 (palmitoyl-protein thioesterase 1) is a small glycoprotein involved in the catabolism of lipid-modified proteins during lysosomal degradation. The encoded enzyme removes thioester-linked fatty acyl groups such as palmitate from cysteine residues. Defects in PPT1 are a cause of infantile neuronal ceroid lipofuscinosis 1 (CLN1, or INCL) and neuronal ceroid lipofuscinosis 4 (CLN4). Two transcript variants encoding different isoforms have been found for PPT1.

Research Areas: Signal Transduction; Metabolism

Target Protein: PPT1

Applications: IHC-p, ELISA

Reactivity: Human, Mouse, Rat

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: CLN1 Antibody

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

Molecular Weight (Da): 34193

UniProt Accession: Human: P50897; Mouse: O88531; Rat: P45479

Synonyms: PPT1; PPT; Palmitoyl-protein thioesterase 1; PPT-1; Palmitoyl-protein hydrolase 1

GeneID: Human: 5538; Mouse: 19063; Rat: 29411

Research Use Only