Product Description

CLPX Rabbit Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: ES17370-50, ES17370-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: The protein encoded by this gene is part of a protease found in mitochondria. This protease is ATP-dependent and targets specific proteins for degradation. The protease consists of two heptameric rings of the CLPP catalytic subunit sandwiched between two hexameric rings of the chaperone subunit encoded by this gene. Targeted proteins are unwound by this protein and then passed on to the CLPP subunit for degradation. Two transcript variants, one protein-coding and the other non-protein coding, have been found for this gene. [provided by RefSeq, Nov 2015],

Reactivity: Human, Mouse, Rat

Host: Rabbit

Applications: WB

Clonality: Polyclonal

Immunogen: Synthesized peptide derived from human CLPX AA range: 328-378

Isotype: IgG

Target: CLPX

Specificity: This antibody detects endogenous levels of CLPX at Human/Mouse/Rat

Dilution: WB 1：500-2000

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

Concentration: 1 mg/ml,

Formlation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Expression: Higher expression in skeletal muscle and heart and to a lesser extent in liver, brain, placenta, lung, kidney and pancreas,

Molecular Weight (Da): 70kD

Function: Function: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of clpP
Similarity: Belongs to the clpX chaperone family
Subunit: Heterodimer of clpP and clpX
Tissue Specificity: Higher expression in skeletal muscle and heart and to a lesser extent in liver, brain, placenta, lung, kidney and pancreas

Subcellular Location: Mitochondrion Mitochondrion matrix, mitochondrion nucleoid

Storage and Stability: -20°C/1 year

Gene Name: CLPX

Protein Name: CLPX

Mouse Gene ID: 270166

Mouse SwissProt Number: Q9JHS4

Rat Gene ID: 300786

Rat SwissProt Number: Q5U2U0

Research Use Only