Product Description

CMBL Rabbit Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: ES17367-50, ES17367-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: CMBL (EC 3.1.1.45) is a cysteine hydrolase of the dienelactone hydrolase family that is highly expressed in liver cytosol. CMBL preferentially cleaves cyclic esters, and it activates medoxomil-ester prodrugs in which the medoxomil moiety is linked to an oxygen atom (Ishizuka et al., 2010 [PubMed 20177059]).[supplied by OMIM, Apr 2010],

Reactivity: Human, Mouse, Rat

Host: Rabbit

Applications: WB

Clonality: Polyclonal

Immunogen: Synthesized peptide derived from human CMBL AA range: 136-186

Isotype: IgG

Target: CMBL

Specificity: This antibody detects endogenous levels of CMBL at Human/Mouse/Rat

Dilution: WB 1：500-2000

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

Concentration: 1 mg/ml,

Formlation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Expression: Widely expressed, with highest levels in liver, followed by kidney, small intestine and colon, Present in liver and intestine (at protein level),

Molecular Weight (Da): 27kD

Fields: Metabolic pathways

Function: Similarity: Belongs to the dienelactone hydrolase family

Subcellular Location: Cytoplasm, cytosol

Storage and Stability: -20°C/1 year

Gene Name: CMBL

Protein Name: CMBL

Mouse Gene ID: 69574

Mouse SwissProt Number: Q8R1G2

Rat Gene ID: 310201

Rat SwissProt Number: Q7TP52

Research Use Only