Product Description

CNDH2 Rabbit Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: ES17350-50, ES17350-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: This gene encodes one of the non-SMC subunits of the condensin II complex. This complex plays an essential role in mitotic chromosome assembly. Alternate splicing of this gene results in multiple transcript variants.[provided by RefSeq, May 2010],

Reactivity: Human, Mouse, Rat

Host: Rabbit

Applications: WB

Clonality: Polyclonal

Immunogen: Synthesized peptide derived from human CNDH2 AA range: 501-551

Isotype: IgG

Target: CNDH2

Specificity: This antibody detects endogenous levels of CNDH2 at Human/Mouse/Rat

Dilution: WB 1：500-2000

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

Concentration: 1 mg/ml,

Formlation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Molecular Weight (Da): 67kD

Function: Function: Regulatory subunit of the condensin-2 complex, a complex that seems to provide chromosomes with an additional level of organization and rigidity and in establishing mitotic chromosome architecture. May play a role in lineage-specific role in T-cell development
PTM: Phosphorylated upon DNA damage, probably by ATM or ATR
Similarity: Belongs to the CND2 H2 (condensin-2 subunit 2) family
Subcellular Location: Distributed along the arms of chromosomes assembled in vivo and in vitro
Subunit: Component of the condensin-2 complex, which contains the smc2 and smc4 heterodimer, and three non SMC subunits, ncapg2, ncaph2 and ncapd3 that probably regulate the complex

Subcellular Location: Nucleus Chromosome Distributed along the arms of chromosomes assembled in vivo and in vitro

Storage and Stability: -20°C/1 year

Gene Name: NCAPH2 CAPH2

Protein Name: CNDH2

Mouse Gene ID: 52683

Mouse SwissProt Number: Q8BSP2

Rat Gene ID: 300149

Rat SwissProt Number: Q4V8I2

Research Use Only