Product Description

CNNM4 Rabbit Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: ES17348-50, ES17348-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: This gene encodes a member of the ancient conserved domain containing protein family. Members of this protein family contain a cyclin box motif and have structural similarity to the cyclins. The encoded protein may play a role in metal ion transport. Mutations in this gene are associated with Jalili syndrome which consists of cone-rod dystrophy and amelogenesis imperfecta. [provided by RefSeq, Feb 2010],

Reactivity: Human, Mouse, Rat

Host: Rabbit

Applications: WB

Alternate Names: Metal transporter CNNM4 (Ancient conserved domain-containing protein 4) (Cyclin-M4)

Clonality: Polyclonal

Immunogen: Synthesized peptide derived from human CNNM4 AA range: 18-68

Isotype: IgG

Target: CNNM4

Specificity: This antibody detects endogenous levels of CNNM4 at Human/Mouse/Rat

Dilution: WB 1:500-2000

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

Concentration: 1 mg/ml,

Formlation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.358% sodium azide.

Expression: Widely expressed, Highly expressed in heart,

Observed Band (KD): 85kD

Function: Function: Probable metal transporter. The interaction with the metal ion chaperone COX11 suggests that it may play a role in sensory neuron functions
Miscellaneous: Shares weak sequence similarity with the cyclin family, explaining its name. However it has no cyclin-like function in vivo
Similarity: Belongs to the ACDP family
Similarity: Contains 2 CBS domains
Subunit: Interacts with COX11
Tissue Specificity: Widely expressed. Highly expressed in heart

Subcellular Location: Cell membrane, Multi-pass membrane protein

Storage and Stability: -20°C/1 year

Gene Name: CNNM4 ACDP4 KIAA1592

Protein Name: CNNM4

Mouse Gene ID: 94220

Mouse SwissProt Number: Q69ZF7

Rat Gene ID: 363216

Rat SwissProt Number: P0C588

Research Use Only