Product Description

CNST Rabbit Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: ES17345-50, ES17345-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: Targeting of numerous transmembrane proteins to the cell surface is thought to depend on their recognition by cargo receptors that interact with the adaptor machinery for anterograde traffic at the distal end of the Golgi complex. Consortin (CNST) is an integral membrane protein that acts as a binding partner of connexins, the building blocks of gap junctions, and acts as a trans-Golgi network (TGN) receptor involved in connexin targeting to the plasma membrane and recycling from the cell surface (del Castillo et al., 2010 [PubMed 19864490]).[supplied by OMIM, Jun 2010],

Reactivity: Human, Mouse

Host: Rabbit

Applications: WB

Clonality: Polyclonal

Immunogen: Synthesized peptide derived from human CNST AA range: 296-346

Isotype: IgG

Target: CNST

Specificity: This antibody detects endogenous levels of CNST at Human/Mouse

Dilution: WB 1：500-2000

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

Concentration: 1 mg/ml,

Formlation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Molecular Weight (Da): 80kD

Subcellular Location: Cell membrane, Single-pass membrane protein Golgi apparatus, trans-Golgi network membrane, Single-pass membrane protein Cytoplasmic vesicle, secretory vesicle Located predominantly in the trans-Golgi network Probably trafficks between the trans-Golgi network and the cell membrane via the secretory pathway

Storage and Stability: -20°C/1 year

Gene Name: CNST C1orf71

Protein Name: CNST

Mouse Gene ID: 226744

Mouse SwissProt Number: Q8CBC4

Research Use Only