Product Description

COLA1 Rabbit Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: ES17335-50, ES17335-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: This gene encodes the alpha chain of type XXI collagen, a member of the FACIT (fibril-associated collagens with interrupted helices) collagen family. Type XXI collagen is localized to tissues containing type I collagen and maintains the integrity of the extracellular matrix. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016],

Reactivity: Human, Rat, Mouse,

Host: Rabbit

Applications: WB

Alternate Names: Collagen alpha-1(XXI) chain

Clonality: Polyclonal

Immunogen: Synthesized peptide derived from human COLA1 AA range: 101-151

Isotype: IgG

Target: COLA1

Specificity: This antibody detects endogenous levels of COLA1 at Human

Dilution: WB 1:500-2000

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

Concentration: 1 mg/ml,

Formlation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.244% sodium azide.

Expression: Highly expressed in lymph node, jejunum, pancreas, stomach, trachea, testis, uterus and placenta, moderately expressed in brain, colon, lung, prostate, spinal cord, salivary gland and vascular smooth-muscle cells and very weakly expressed in heart, liver, kidney, bone marrow, spleen, thymus, skeletal muscle, adrenal gland and peripheral leukocytes, Expression in heart was higher in the right ventricle and atrium than in the left ventricle and atrium,

Observed Band (KD): 105kD

Fields: Protein digestion and absorption

Function: Caution: The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data
Developmental Stage: Highest expression observed at the fetal stage. Expressed by smooth-muscle cells in the artery wall in a PDGF-dependent way
Induction: Stimulated by platelet-derived growth factor (PDGF)
Similarity: Belongs to the fibril-associated collagens with interrupted helices (FACIT) family
Similarity: Contains 1 TSP N-terminal (TSPN) domain
Similarity: Contains 1 VWFA domain
Similarity: Contains 6 collagen-like domains
Subcellular Location: Found in the extracellular matrix component of blood vessel walls and in the cytoplasm of cultured human aortic smooth muscle
Tissue Specificity: Highly expressed in lymph node, jejunum, pancreas, stomach, trachea, testis, uterus and placenta, moderately expressed in brain, colon, lung, prostate, spinal cord,

Subcellular Location: Secreted, extracellular space, extracellular matrix Cytoplasm Found in the extracellular matrix component of blood vessel walls and in the cytoplasm of cultured human aortic smooth muscle

Storage and Stability: -20°C/1 year

Gene Name: COL21A1 COL1AL FP633

Protein Name: COLA1

Research Use Only