Product Description

Collagen I Recombinant Rabbit mAb

Sizes: 50μl, 100μl

Catalogue Numbers: BS45858-50, BS45858-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: This gene encodes the pro-alpha1 chains of type I collagen whose triple helix comprises two alpha1 chains and one alpha2 chain. Type I is a fibril-forming collagen found in most connective tissues and is abundant in bone, cornea, dermis and tendon. Mutations in this gene are associated with osteogenesis imperfecta types I-IV, Ehlers-Danlos syndrome type VIIA, Ehlers-Danlos syndrome Classical type, Caffey Disease and idiopathic osteoporosis. Reciprocal translocations between chromosomes 17 and 22, where this gene and the gene for platelet-derived growth factor beta are located, are associated with a particμlar type of skin tumor called dermatofibrosarcoma protuberans, resμlting from unregμlated expression of the growth factor. Two transcripts, resμlting from the use of alternate polyadenylation signals, have been identified for this gene. [provided by R. Dalgleish, Feb 2008]

Category: Primary Antibody

Reactivity: Human

Host: Rabbit

Applications: WB, IHC, ICC/IF

Alternate Names: OI1, OI2, OI3, OI4, EDSC

Clonality: Monoclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: A synthetic peptide of human Collagen I

Dilution: WB: 1:1000-1:5000 IHC: 1:200-1:1000 ICC/IF: 1:200-1:2000

Purification: Affinity Purification

Specificity: IgG

Molecular Weight: 139 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: P02452

Product: Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

Research Use Only