Product Description

Collagen V α1 (Cleaved-Ala1605) Rabbit Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA23656-50, RA23656-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: disease:Defects in COL5A1 are a cause of Ehlers-Danlos syndrome type 1 (EDS1) [MIM:130000]; also known as Ehlers-Danlos syndrome gravis or severe classic type Ehlers-Danlos syndrome. EDS is a connective tissue disorder characterized by hyperextensible skin, atrophic cutaneous scars due to tissue fragility and joint hyperlaxity. EDS1 is the severe form of classic Ehlers-Danlos syndrome., disease:Defects in COL5A1 are a cause of Ehlers-Danlos syndrome type 2 (EDS2) [MIM:130010]; also known as Ehlers-Danlos syndrome mitis or mild classic type Ehlers Danlos syndrome., function:Type V collagen is a member of group I collagen (fibrillar forming collagen). It is a minor connective tissue component of nearly ubiquitous distribution. Type V collagen binds to DNA, heparan sulfate, thrombospondin, heparin, and insulin., PTM:Prolines at the third position of the tripeptide repeating unit (G-X-Y) are hydroxylated in some or all of the chains., PTM:Sulfated on 40% of tyrosines., similarity:Belongs to the fibrillar collagen family., similarity:Contains 1 laminin G-like domain., similarity:Contains 1 TSP N-terminal (TSPN) domain., subunit:Trimers of two alpha 1 (V) and one alpha 2 (V) chains in most tissues and trimers of one alpha 1 (V), one alpha 2 (V), and one alpha 3 (V) chains in placenta. Interacts with CSPG4.,

Reactivity: Human, Rat, Mouse

Host: Rabbit

Applications: WB, ELISA

Alternate Names: Collagen alpha-1 (V) chain

Clonality: Polyclonal

Dilution: WB 1:1000-2000 ELISA 1:5000-20000

Molecular Weight: 175 202

Protein Molecular Weight (kDa): 175 202

Storage: -20°C/1 year

Human Gene ID: 1289

Human SwissProt Number: P20908

Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Research Use Only