Complement C3 Rabbit PolymAb®
Sizes: 20μL, 100μL
Catalogue Numbers: A26625PM-20, A26625PM-100
Citations, Manuals and MSDS Available upon request.
Background: Complement component C3 plays a central role in the activation of complement system. Its activation is required for both classical and alternative complement activation pathways. The encoded preproprotein is proteolytically processed to generate alpha and beta subunits that form the mature protein, which is then further processed to generate numerous peptide products. The C3a peptide, also known as the C3a anaphylatoxin, modulates inflammation and possesses antimicrobial activity. Mutations in this gene are associated with atypical hemolytic uremic syndrome and age-related macular degeneration in human patients.
Category: Monoclonal Antibodies
Applications: WB, ELISA
Cross-reactivity: Human, Mouse, Rat
Protein Weight: 186kDa
Observed Molecular Weight: 115kDa/187kDa
Immunogen: Recombinant protein (or fragment) .
Species: Human/Mouse
GeneID: 718/12266
SWISS: P01024/P01027
Alternate Names: ASP; C3a; C3b; AHUS5; ARMD9; CPAMD1; HEL-S-62p
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol and 0.05% BSA, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
Recommended Dilutions: WB, 1:1000 - 1:6000 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Research Areas: Signal Transduction, G protein signaling, G-Protein-Coupled ReceptorsGPCR, Immunology Inflammation, Cell Intrinsic Innate Immunity Signaling Pathway.
NCBI Alias: C3
Research Use Only