COX1 Polyclonal Antibody - BT-AP02145

COX1 Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP02145-20, BT-AP02145-50, BT-AP02145-100

Citations, Manuals and MSDS Available upon request.

Background: PTGS1 is one of two genes encoding similar enzymes that catalyze the conversion of arachinodate to prostaglandin. Prostaglandin-endoperoxide synthase 1 regulates angiogenesis in endothelial cells, and is inhibited by nonsteroidal anti-inflammatory drugs such as aspirin. Based on its ability to function as both a cyclooxygenase and as a peroxidase, prostaglandin-endoperoxide synthase 1 has been identified as a moonlighting protein. Prostaglandin-endoperoxide synthase 1 may promote cell proliferation during tumor progression. Alternative splicing results in multiple transcript variants.

Research Areas: Immunology

Target Protein: PTGS1

Applications: WB

Reactivity: Human

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: COX1 Antibody

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

Molecular Weight (Da): 68656

UniProt Accession: Human: P23219; Mouse: P22437; Rat: Q63921

Synonyms: PTGS1; COX1; Prostaglandin G/H synthase 1; Cyclooxygenase-1; COX-1; Prostaglandin H2 synthase 1; PGH synthase 1; PGHS-1; PHS 1; Prostaglandin-endoperoxide synthase 1

GeneID: Human: 5742; Mouse: 19224; Rat: 24693

Research Use Only