Product Description

COX7B Rabbit Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: ES17272-50, ES17272-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: Cytochrome c oxidase (COX), the terminal component of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. This component is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may function in the regulation and assembly of the complex. This nuclear gene encodes subunit VIIb, which is highly similar to bovine COX VIIb protein and is found in all tissues. This gene may have several pseudogenes on chromosomes 1, 2, 20 and 22. [provided by RefSeq, Jun 2011],

Reactivity: Human, Rat, Mouse,

Host: Rabbit

Applications: IHC, ELISA

Alternate Names: Cytochrome c oxidase subunit 7B, mitochondrial (Cytochrome c oxidase polypeptide VIIb)

Clonality: Polyclonal

Immunogen: Synthesized peptide derived from human COX7B AA range: 20-100

Isotype: IgG

Target: COX7B

Specificity: This antibody detects endogenous levels of human COX7B

Dilution: IHC-p 1:50-200, ELISA(peptide)1:5000-20000

Purification: The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.

Concentration: 1 mg/ml,

Formlation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Expression: Heart, Ovary,

Fields: Oxidative phosphorylation, Metabolic pathways, Cardiac muscle contraction, Thermogenesis, Non-alcoholic fatty liver disease, Alzheimer disease, Parkinson disease, Amyotrophic lateral sclerosis, Huntington disease, Prion disease, Pathways of neurodegeneration - multiple diseases, Chemical carcinogenesis - reactive oxygen species, Diabetic cardiomyopathy

Function: Function: This protein is one of the nuclear-coded polypeptide chains of cytochrome c oxidase, the terminal oxidase in mitochondrial electron transport
Similarity: Belongs to the cytochrome c oxidase VIIb family

Subcellular Location: Mitochondrion inner membrane, Single-pass membrane protein

Storage and Stability: -20°C/1 year

Gene Name: COX7B

Protein Name: COX7B

Research Use Only