Product Description

Crystallin-αC Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA23830-50, RA23830-100

Citations, Manuals and MSDS Available upon request.

Background: heat shock protein family B (small) member 8 (HSPB8) Homo sapiens The protein encoded by this gene belongs to the superfamily of small heat-shock proteins containing a conservative alpha-crystallin domain at the C-terminal part of the molecule. The expression of this gene in induced by estrogen in estrogen receptor-positive breast cancer cells, and this protein also functions as a chaperone in association with Bag3, a stimulator of macroautophagy. Thus, this gene appears to be involved in regulation of cell proliferation, apoptosis, and carcinogenesis, and mutations in this gene have been associated with different neuromuscular diseases, including Charcot-Marie-Tooth disease. [provided by RefSeq, Jul 2008],

Condition: PBS, pH 7.4, containing 0.5%BSA, 0.02% sodium azide as Preservative and 50% Glycerol.

Storage Instructions: -20°C/1 year

Recommended dilutions: WB: 1:500-1000

Alternative Names: HSPB8; CRYAC; E2IG1; HSP22; PP1629; Heat shock protein beta-8; HspB8; Alpha-crystallin C chain; E2-induced gene 1 protein; Protein kinase H11; Small stress protein-like protein HSP22; YM3454

Applications: WB

Species Cross-Reactivity: Human

GeneID (Human): 26353

Protein MW (KDa): 22

SWISS: Q9UJY1

Source: Rabbit

Research Use Only