Product Description

CST9 Rabbit Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: ES17200-50, ES17200-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins and the kininogens. The type 2 cystatin proteins are a class of cysteine proteinase inhibitors found in a variety of human fluids and secretions, where they appear to provide protective functions. The cystatin locus on chromosome 20 contains the majority of the type 2 cystatin genes and pseudogenes. This gene is located in the cystatin locus and encodes a secreted protein that may play a role in hematopoietic differentiation or inflammation. [provided by RefSeq, Jul 2008],

Reactivity: Human, Mouse

Host: Rabbit

Applications: WB

Clonality: Polyclonal

Immunogen: Synthesized peptide derived from human CST9 AA range: 108-158

Isotype: IgG

Target: CST9

Specificity: This antibody detects endogenous levels of CST9 at Human/Mouse

Dilution: WB 1：500-2000

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

Concentration: 1 mg/ml,

Formlation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Expression: Expressed in heart, placenta, lung, liver, skeletal muscle and pancreas (PubMed:12535658), Not expressed in brain (PubMed:12535658), Expressed in epididymis, kidney, testis, spinal cord, and thymus with a strong expression in epididymis and kidney and a weak expression in the spinal cord and thymus (PubMed:20565543),

Molecular Weight (Da): 17kD

Function: Function: May play a role in hematopoietic differentiation or inflammation
Induction: Up-regulated by LPS, in some cancer cells such as promyelocytic leukemia cells (HL-60) or myelomonocytic leukemia cells (U-937)
Similarity: Belongs to the cystatin family
Subcellular Location: May be targeted through the Golgi via the secretory pathway
Tissue Specificity: Expressed in heart, placenta, lung, liver, skeletal muscle and pancreas. Not expressed in brain. Barely expressed in tumor cell lines except for breast adenocarcinoma MCF-7 cells and U251 cells

Subcellular Location: Secreted May be targeted through the Golgi via the secretory pathway

Storage and Stability: -20°C/1 year

Gene Name: CST9 CLM

Protein Name: CST9

Mouse Gene ID: 13013

Mouse SwissProt Number: Q9Z0H6

Research Use Only